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The administration of NMN, similar to the exogenous addition of NAD + , led to increases in OCR and mitochondrial function in neuroblastoma cells 55

Acknowledgements We thank Junko Sato and Mayumi Suda and the Biomedical Research Unit of Tohoku University Hospital for technical assistance with the experiments

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The research also noted that these effects occurred without the hypoglycemia sometimes saw with insulin or native IGF-1, suggesting a more favorable safety profile for research uses