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(2020) demonstrated that Citrus latifolia increases the production of prostaglandin F2, which acts on prostaglandin receptors to reduce the menstrual volume and inhibits the release of proinflammatory cytokines such as TNF- (Ekstrm et al., 1991)

Genistein was proposed as a Plk1 inhibitor, which effectively downregulates the expression of multidrug resistance protein 1 and multidrug resistance-associated protein 1, key factors inducing chemoresistance in paclitaxel-resistant cancer cells (Shin et al., 2019)

Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M, Hui L et al

Comparing Glutathione in the Plasma of Vegetarian and Omnivore Populations

In the mitochondria choline is oxidized to betaine aldehyde by choline dehydrogenase (encoded by the CHDH gene)

This multi-pathway approach is what differentiates OGF from many single-nutrient formulas that focus on only one aspect of antioxidant support