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Electroacupuncture at the Tianshu (ST25) point can alleviate PD-associated constipation by enhancing the autophagic state within the enteric nervous system, protecting enteric neuronal function, and regulating intestinal motility

Cys 156 of CAV1 is a known palmitoylation site 21 as well as a nitrosylation target 22

In CeA neurons, direct parabrachial glutamatergic input to corticotropin-releasing factor (CRF) neurons is insensitive to KORs

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Further, by the time candidate predictive biomarkers were proposed and combinatorial treatment protocols designed to counter compensatory signaling pathways, pharmaceutical development of most IGF-1R targeting agents for oncology had ceased

Proc Natl Acad Sci U S A 88(13):55135517 Wang L-C, Jung S-M, Chen K-Y, Wang T-Y, Li C-H (2015) Temporal-spatial pathological changes in the brains of permissive and non-permissive hosts experimentally infected with Angiostrongylus cantonensis