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Key proteins involved in lipoprotein metabolism, such as PCSK9, angiopoietin-related protein 3, cholesteryl ester transfer protein and apolipoprotein(a), have been identified as viable targets for therapeutic intervention through observational and genetic studies

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In particular, CNAA was identified as an optimal matrix in positive ion mode, whereas CNDA demonstrated suitability for the analysis of neutral lipids, including diacylglycerols (DAGs) and TAGs