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doi: 10.1111/j.1476-5381.2012.02068.x [DOI] [PMC free article] [PubMed] [Google Scholar] 60

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Bottom line Phentermine and metformin are two drugs that can help patients lose weight, although they arent always the best combination

Reduced response to inhaled beta-2 agonists (e.g., salbutamol), which may be less effective in relieving bronchospasm in patients taking non-selective beta-blockers
