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In vivo studies have shown that MSM can increase the ileal villus height and villus height-to-crypt ratio [10], regulate the gut microbiota by reducing Escherichia coli and increasing Lactobacillus populations [9,49], decrease the severity of ethanol/HCl-induced gastric mucosal injury [23], improve intestinal damage [35], and increase the intestinal transport capacity of animals [17]

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