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rs1169299 and rs10466245 were also related to diabetes in DIAGRAM and HDL-cholesterol in GLGC respectively but did not reach genome-wide significance

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[DOI] [PubMed] [Google Scholar] 1116.Oliveira A., Rodrguez-Artalejo F., Lopes C

1 Caenorhabditis elegans nuclear hormone receptors control metabolism, stress responses, and aging Nuclear hormone receptors (NHRs) are a family of metazoan transcription factors whose activity can be altered by ligands, including steroid hormones, fatty acid like molecules, and other compounds (Sever and Glass, 2013

however, the dose-response meta-analysis indicated that prolonged LC intake significantly increased estrogen levels