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Psoriasis patients were found to have increased amounts of LL-37 in their skin lesions, and it appears to promote inflammation by activating plasmacytoid dendritic cells and inducing an autoimmune response-like process

Considering that the cold face test, inhaling cold air and whole body cooling accompany increased blood pressure, it would be interesting to investigate whether cold exposure suppresses blood pressure decline during sleep

Within the gastrointestinal system, it has been investigated for its role in preserving epithelial continuity and local perfusion

Tirzepatide reduces insulin secretion and improves sensitivity, while growth hormone can increase insulin resistance transiently

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Wassum, Cely, Balleine, & Maidment, 2011