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Lussu M, Noto A, Masili A, Rinaldi AC, Dess A, Angelis MD, et al

Specifications Synonyms: Copper Tripeptide-1, GHK-Cu, Gly-His-Lys-Cu Molecular formula: CHNO Cu Molecular weight: 340.9 g/mol Class: Regenerative copper-binding tripeptide Primary research domains: Tissue repair, wound healing, anti-inflammatory signaling, fibrosis, angiogenesis, skin biology, hair-follicle regeneration, neuroprotection Mechanism of Action Copper Mobilization & Regenerative Signaling 1

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Mechanistically, the upregulation of CTR1 required Smads-dependent TGF- signaling pathway and Smad3 directly binded to the promoter of CTR1 in renal fibroblast cells using chromatin immunoprecipitation