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Additionally, their metabolism can lead to inactivation and loss of biological activity, making their direct use limited 25

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8/20 patients were female and 75% postmenopausal

That conjugate is then converted into a mercapturic acid adduct in vivo and is then excreted in the urine (Moss et al., 1985
[DOI] [PMC free article] [PubMed] [Google Scholar] 557.Adlard PA, et al

Additionally, there are no regulations for the control of therapeutic drugs based on exosomes that consider safety, effectiveness, and quality control, highlighting the urgent need for standardized methods and principles to manage these molecules
