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22 Considering the negative side effects of systemic corticosteroids (osteoporosis, hyperglycemia, edema, weight gain, depression, etc.) and the lack of evidence that they alter the natural history of hepatic sarcoidosis, their use is best reserved for patients who did not respond successfully to UDCA therapy, that is, no response after 3 months of therapy or patients with significant elevation in liver enzymes, portal hypertension, or unexplained hepatic decompensation with cirrhosis secondary to sarcoidosis

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At a time when our skin is increasingly exposed to environmental stress and free radicals, it provides a protective barrier

When used as directed and combined with healthy lifestyle practices, it can significantly improve digestive comfort and quality of life