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Maage, Amund
[13:05] Jamie Well, so how was this whole opinion based on this one study from the 1930s and just repeated ad nauseam for decades
Among them, DNL201, a CNS-penetrant LRRK2 inhibitor, has been shown in preclinical studies to effectively reduce LRRK2 activity and restore lysosomal function
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While retaining their binding to cartilage, these fragments were able to carry payloads such as an MMP-cleavable form of viral IL-10 60 and soluble TNF receptor II, 33 enabling the in vivo imaging of murine OA cartilage
