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The degenerative process of intervertebral discs is often accompanied by the overexpression of matrix metalloproteinases (MMP3, MMP13) and inflammatory factors (IL-1, IL-6, IL-8, PEG2, TNF-) (Wang et al., 2020)

Teplizumab, a monoclonal antibody that will be marketed under the brand name Tzield from pharmaceutical companies ProventionBio and Sanofi, is administered through intravenous infusion

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The design of the sleeping fusion peptide plasmid is a strategic approach to creating a novel biological tool that combines the capabilities of cell-penetrating peptides, a fluorescent marker, and a DSIP for targeted research applications, particularly in the study of sleep mechanisms and potentially therapeutic interventions

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The largest number of genes (96) that exhibited altered expression (cut-off 1.50) in response to Semax administration was detected 3 h after the onset of ischemia (Additional file 1)