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Researchers and medical providers still dont fully understand the Herxheimer reaction, but they have a theory

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Christensen B.C., Kelsey K.T., Zheng S., Houseman E.A., Marsit C.J., Wrensch M.R., Wiemels J.L., Nelson H.H., Karagas M.R., Kushi L.H., et al

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Emodin and other AQs released into the soil create chemically hostile zones of exclusion where native species experience reduced germination and growth, potentially facilitating monoculture formation ( Senna tora shows stimulus-dependent decoupling between branches: jasmonate- and wounding-related signaling preferentially amplifies flavonoid responses, while anthraquinone accumulation can be less responsive on the same timescale

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