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TMAO Metabolism Choline, L-carnitine, betaine, and other choline-containing compounds are the major nutrient precursors of gut microbe-dependent TMAO, a pro-atherogenic metabolite (Wang et al., 2011

Various preclinical models have been created that are showing the impact of metabolism on brain function and in particular the role that impaired metabolism plays in the neurodegeneration processes

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However, the organism's low carnitine diet stimulates the body to produce more endogenous carnitine

BMC Neurosci