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Figure 5 Zone Specific Metabolism Paracetamol is metabolized in the liver predominantly by CYP enzymes where it is metabolized to the cytotoxic intermediate NAPQI, which in turn depletes glutathione, leading to cell death after an overdose (McCarty et al., Figure 6)
Technically, vitamins are the essential nutrients A, B, C, D, E, and K
It is important to recognize that ethnic background and a traditional diet rich in folate have a significant impact on the results of current studies
10.1038/s41586-022-05022-3 74 MurphyT
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