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Generally, a dose of 1,000 to 2,000 mg per day, taken before exercise or spread throughout the day, is a good starting point for most individuals
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[DOI] [PubMed] [Google Scholar] 109.Louwerse E.S., Weverling G.J., Bossuyt P.M., Meyjes F.E., de Jong J.M
In stark contrast, only 3.5% of the untreated control group achieved a similar reduction in fatigue
Another study reported increased venous tone in patients with extensive varicose veins following a single administration of 150 mg proanthocyanidins (MacKay 2001)
