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Glutathione is a naturally occurring tripeptide composed of glutamine, cysteine, and glycine, and is widely recognized as a master antioxidant in the body

FOXO4-DRI is a D-retro-inverso (DRI) peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells

29 , 417429.e414 (2019)

Cystine starvation promotes a non-canonical function of the glutathione synthesis machinery NRF2-mediated metabolism also promotes cell survival

Conversely, high encapsulation efficiency can result in drug overdosing, potentially leading to adverse side effects

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