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Description
It is unclear how the immunomodulatory effects of hydroxychloroquine may influence the relative efficiency of transduction of AAV-delivered transgenes to the RPE or photoreceptors given this RPE-predominant tissue distribution from systemically administered hydroxychloroquine
Front Physiol (2020) 11:543564
Typically, patients require an initial loading period of 8 weeks or anywhere between 3 9 months to achieve full benefits
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In addition, we use isotopic labeling experiments to demonstrate that BCKDH is also inhibited in a NOS2-dependent way
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