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The multifunctional docking site of MET recruits to the plasma membrane stereotypical adaptor/signaling molecules such as Gab1, Grb2, SPH2, phosphoinositide-3-kinase (PI-3K), Src, phospholipase c gamma (PLC), Shc, and signal transducer and activator of transcription 3 (STAT3) (Ponzetto et al., 1994

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Sindsdien zijn er meer dan honderd peer-reviewed publicaties verschenen over de pre-klinische karakterisering van het peptide, met name in de context van: Gastro-intestinale weefselintegriteit , modellen voor mucosale beschadiging en herstel Tendon- en ligament-onderzoek , in vitro studies over cellulaire migratie en tendon-fibroblast-uitgroei Vasculaire respons , angiogenese-modellen en endotheel-functie Het mechanisme is nog niet volledig opgehelderd

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Contrary to this, no difference between the control values and the analyzed agent was observed in groups treated with all three H2-blockers