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105 This approach has the potential to provide a durable solution for patients with HeFH, as well as polygenic hypercholesterolaemia, and might be useful for patients with low adherence to therapy and for patients in whom statins are deferred due to adverse side effects

4.1 Drupaceous bioactive phytochemicals The drupe serves as the principal phytochemical reservoir in Hippophae species, exhibiting high nutraceutical density and marked biofunctional properties that garner considerable interest in functional food development and pharmacognosy research

IMR-90 cell line displayed a decreased expression of both proteins, with levels similar to A549 shXPF cells, which could explain its reduced cell viability

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2 Materials and methods 2.1 Patient selection Fifty-eight patients were retrospectively analyzed from the database of patients with epilepsy who have been prescribed MAD therapy at the UW Health Adult Neurology Ketogenic Diet Therapy Clinic