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Surfactant alteration and replacement in acute respiratory distress syndrome

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These factors lead to an easier buildup of free radicals and accumulation of toxins, which the body copes with with its natural first line of defense of antioxidants, which often may not be sufficient

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In both CKD and ESRD patients, several metabolic alterations, including acidosis, systemic inflammation and hormonal dysregulation, together with comorbidities and multidrug therapies, can lead to malnutrition with subsequent folic acid and vitamin B12 deficiency