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High concentration of GSH in many tumors together with its high reactivity leads towards utilization of GSH as an activator of prodrugs, possibly leading to GSH depletion as well as release of toxic chemotherapeutic agents
DOI: 10.11138/FNeur/2013.28.4.297
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Intracellular regulation of Ca 2+ is maintained by the action of ATP-dependent pumps, which trigger mitochondrial activity and accompanying enhanced ROS formation (Surmeier et al
