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Prostaglandin E1 has diverse biological activities, including vasodilation [58], inhibition of intracellular reactive oxygen species, improvement of mitochondrial membrane potential, and inhibition of cell apoptosis [59]

They dissolve in the digestive system like standard tablets and work well for those who prefer straightforward supplementation

Total plasma carnitine concentrations were determined in 48 out of 69 patients and were found to be rather low, as was the percentage of free carnitine

Ethics declarations Ethical approval Study on therapeutic approach to fibromyalgia received approval from Bari Regional Ethical Committee at IRCSS Giovanni Paolo II, Bari