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Receptor downregulation typically occurs in response to chronic overexposure to an agonist, leading to decreased receptor density to prevent cellular overstimulation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 240.Maddocks O.D.K., Athineos D., Cheung E.C., Lee P., Zhang T., van den Broek N.J.F., Mackay G.M., Labuschagne C.F., Gay D., Kruiswijk F., et al

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