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NFPS (ALX5407) administered to rats in a maximal electroshock threshold (MEST) model showed positive effects, increasing the seizure threshold with doses ranging from 1.0 to 32 mg/kg (p.o.) (Kalinichev et al
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Antitumour therapy can contribute to seizure control, and antiepileptic drugs might have beneficial effects on tumours
In addition, ferroptosis, as a form of inflammatory cell death, is associated with the release of DAMPs, which can trigger the innate immune system and activate the NF-B pathway through AGER [95, 109]
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