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Ueland PM

A sixth ligand, possibly a hydroxide ion, also participates in stabilizing the Mn 2+ conformation and facilitating the next catalytic round

10.1007/s00018-020-03473-3

Second, translational development should focus on dual-functional nanocarriers incorporating A-targeting peptides and RVG29 brain-homing peptides, delivering GPX4 activators or iron chelators with pH/ROS-responsive release to ensure lesion-specific delivery and avoid neurotransmitter synthesis impairment from non-specific iron depletion

doi: 10.1016/j.freeradbiomed.2006.11.003 99 PapadopoulosC.KirchnerP.BugM.GrumD.KoerverL.SchulzeN.et al

