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A 18-glycyrrhetinic acid conjugate with Vorinostat degrades HDAC3 and HDAC6 with improved antitumor effects

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In target tissues, such as the liver and the brain, T 4 (the most abundant circulating thyroid hormone) can be converted to T 3 by selenium-containing enzymes known as iodothyronine deiodinases (DIOs) ( Figure 1

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