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References for this information: Dermatologic Therapy, September 2017, pages 293-304 Postepy Dermatologii I Alergologii, August 2019, pages 392-397 Clinical, Cosmetic, and Investigational Dermatology, August 2015, pages 455-461 The Journal of Clinical and Aesthetic Dermatology, January 2017, pages 37-46 Journal of Cosmetic Dermatology, March 2020, pages 660-670 Journal of Italian Dermatology and Venereology, December 2020, pages 744748

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Different cellular ion and water transporters and channels are essential mediators in determining neuronal excitability and synchrony and can do so through alterations in ECS volume and/or through non-ECS volume related mechanisms

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