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VB12 In human metabolism, VB12 (cobalamin) plays a crucial role as a cofactor in the conversion of methylmalonyl-CoA to succinyl-CoA, which is essential for energy production [135]
and Wongkajornsilp A
Oxid Med Cell Longev 2017:132
Rosenkrans, Z
For example, luteolin is effective in therapeutically induced cytotoxicity of cancer cells due to its suppression of cell survival pathways, such as phosphatidylinositol-3-kinase (PI3K)/Akt, NF-B, and X-linked inhibitor of apoptosis protein (XIAP), resulting in the stimulation of apoptosis pathways, including the induction of the p53 tumour suppressor [39]
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