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Cardiovascular risk Factors Predicting the Development of Distal Symmetrical Polyneuropathy in People with Type 1 Diabetes

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[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Zhang J, Zeng W, Han Y, Lee WR, Liou J, Jiang Y

These include hemodynamic overload, ventricular dysfunction secondary to ischemia and structural changes in the ventricular architecture

Although NACs ability to restore intracellular GSH and modulate ferroptotic markers remains mechanistically relevant, its limited benefit in clinical practice suggests a need to prioritize more targeted and potent antioxidants in future therapeutic design

By relaxing the long-only constraint, the investment opportunity set expands significantly, allowing for greater flexibility in portfolio construction