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Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

All the experiments followed the Guidelines of Ethical Standards for Investigation of Experimental Pain in Animals

Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms

In addition, vitamin D has been discussed in relation to thrombosis pathways and coagulation regulation, although these effects appear indirect and are not established as direct anticoagulant actions

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Later, LC3 is recruited to damaged mitochondria by the omegasome protein double FYVE-containing protein 1 (DFCP1), enabling OPTN-mediated initiation of the autophagosome via its LIR [186]