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The corresponding AUC increased significantly from 0685 (0626, 0745) in the traditional risk factor model to 0769 (0716, 0822) when TMAO and its precursors were included (l-carnitine, betaine and choline) ( P = 0032)

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J Am Chem Soc 139(11):40194024 Jezyk MR et al (2006) Crystal structure of Rac1 bound to its effector phospholipase C-beta2

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