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This suppression contributes to an increased number of atretic follicles in PCOS mouse models [110]

DAMPs released by dying hepatocytes, along with PAMPs, stimulate Kupffer cells to upregulate proinflammatory cytokines, leading to the recruitment of neutrophils and macrophages to the liver [40, 41]

doi: 10.1111/j.1365-2125.2007.02881.x

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Our model simulations are reflective of the hepatic GSH environment, agreeing with the supra-pharmacological concentrations of doxorubicin required to illicit comparable GSH depletion in the liver 39

H., Ngong, J