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Overexpression of the histone methyltransferase Ezh2, which catalyzes tri-methylation at H3K27, represses genes involved in astrocyte maintenance, allowing the cell to retain a neural stem cell-like morphology

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The review also documents neuroprotective effects, including peripheral nerve regeneration after transection and counteraction of the otherwise progressing course following traumatic brain injury

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TIP3P water molecules 49 were added to the simulation box (final dimensions 126 x 126 x 186 ) using the VMD Solvate plugin 1.5 (VMD Solvate plugin, Version 1.5

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