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Cortisol deficiency may result in fatigue, sluggishness, and no desire to exercise

Excess stacking disturbs this oscillation, leading to metabolic fatigue, sleep disturbances, or hormonal imbalance

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Didangelos T, Karlafti E, Kotzakioulafi E, Margariti E, Giannoulaki P, Batanis G, Tesfaye S, Kantartzis KJN (2021) Vitamin B12 supplementation in diabetic neuropathy: a 1-year, randomized, double-blind, placebo-controlled trial

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Non-GLP-1 alternatives Metformin: Metformin (Glumetza and Fortamet) is a pill used to treat type 2 diabetes by helping control blood sugar levels