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Modifications of efflux transporter and CYP3A4 activities may explain how supplementation with garlic phytochemicals might hinder the therapeutic efficacy of medications like antiretroviral drugs (162)
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TIMP-2 is a tissue inhibitor for MMP-2, another ECM protein

Water-soluble organosulfur compounds, such as S-allylcysteine and SAMC ( Figure 3 ), are formed from -glutamyl-S-allyl-L-cysteine during long-term incubation of crushed garlic in aqueous solutions, as in the manufacture of aged garlic extracts (see Sources)
Furthermore, comparing Prdx Km for H 2 O 2 with that of GPx and catalase exceeding even the millimolar range [180] suggests that the role of Prdx is rather as a sensor of H 2 O 2 [178] than oxidative stress condition reversal
