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3c,d, AC3-C cells exposed to IL-1 presented a higher number of NSE compared with the same cell type under control condition

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Interestingly, the NCT00071799 study reported that MDS patients treated with 5-Aza (75 mg/m 2 subcutaneously) + BSC exhibited prolonged hematological responses and increased RBC IT compared to those receiving standard chemotherapy (cytarabine + anthracycline) + BSC (median OS: 24.5 months vs 16 months) [346,347,348,349,350]

Also, Cinobufacini, a well-known traditional Chinese medicine extracted from toad skins and venom glands, has a therapeutic effect in HCC (Qi et al., 2018)