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It has been reported that SIRT1 could deacetylase the FOXO transcription factors in vitro and within mammalian cells to increase cellular stress resistance, which is correlated with extended organismal longevity (55)

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However, inhaled free anti-fibrosis agents are highly toxic, easily cleared quickly, and their distribution in the lungs is not specific

MiR-146a mainly regulates the target genes of NF-B related pathways, thereby affecting the process of inflammatory response (Zheng et al., 2020)

From hyperglycemia to AGE-RAGE interaction on the cell surface: a dangerous metabolic route for diabetic patients