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Alcohol-induced oxidative stress end-organ injury [2], [7], [10] is believed to be the results of mitochondrial damage [11], [12], [13], [14], [15] and decrease of ATP production [16]

Acknowledgements Not applicable

Patients with mitochondrial myopathy may show histochemical alterations in their skeletal muscle which indicate mitochondrial dysfunction, although in some patients, the muscle biopsy can appear normal

We performed a review of the English literature regarding the cardiac histopathological patterns associated to the chronic use of EDs

doi:10.3389/fpsyt.2021.664499