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They address different aging mechanisms

doi: 10.3390/microorganisms7030067 118 StewartCJAjamiNJObrienJLHutchinsonDSSmithDPWongMCet al

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Pharmacologic and genetic suppression of GPX4 induces ferroptosis, DNA damage, and decreased cell viability in vitro via a novel mechanism of mTOR signaling pathway inhibition

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And GPX4 is increased in gefitinib-resistant cells