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With an exceptionally high nutritional value, tart cherry juice concentrate has been used for thousands of years, and today tart cherry extract capsules are taken for their incredible health-promoting effects

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FIGURE 2 On the other hand, in addition to its well-known functions, PGC1, a master regulator of mitochondrial biogenesis, positively regulates mitophagy by directly inducing the expression of transcription factor EB (TFEB) that mediates lysosomal biogenesis (Settembre et al., 2011)

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