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Excessive deposition of stiff, cross-linked ECM components including type I/III collagen, fibronectin, and HA alters the biomechanical properties of the hepatic microenvironment

Van Der Velpen et al., 2019

Largest effects were observed in monotherapy vs placebo/no treatment , while head-to-head comparisons did not demonstrate superiority of ALC over antidepressant drugs

The constant, high-volume workload placed on these pumps may eventually cause damage to the renal tubules, which are the structures responsible for this transport [3]

[DOI] [PubMed] [Google Scholar] 23.Moore RD, Romine MW, O'Conner PJ, Tomporowski PD

In contrast, chronic elevations in TMAO, a metabolite derived from LC, have been linked to an increased risk of atherosclerotic cardiovascular disease (ASCVD), particularly in older adults with compromised renal function [64, 65]
