glutathione esters toxicity Glutathione: Antioxidant Properties Dedicated to Nanotechnologies Tumor-targeted glutathione oxidation catalysis with

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Successive decarboxylations (by uroporphyrinogen decarboxylase, UROD) remove four acetate side chains to yield coproporphyrinogen III, which re-enters the mitochondria for oxidative decarboxylation to protoporphyrinogen IX by coproporphyrinogen oxidase (CPOX), followed by aromatization to protoporphyrin IX by protoporphyrinogen oxidase (PPOX)

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DeHart DN, Fang D, Heslop K, Li L, Lemasters JJ, Maldonado EN