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NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells

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References 1.Goki N.H., Tehranizadeh Z.A., Saberi M.R., Khameneh B., Bazzaz B.S.F

however, GSH levels are also influenced by agents or conditions that alter the thiol redox state, that lead to the formation of glutathione S -conjugates or complexes, and/or that disrupt the distribution of GSH among various intracellular organelles

The degree of inflammation of the colon was graded semiquantitatively from 0 to 11 according to described criteria (Appleyard and Wallace, 1995) taking into consideration (1) loss of mucosal architecture (score 03), (2) cellular infiltration (score 03) (3) muscle thickening (score 03), (4) crypt abscess formation (score 01) and (5) goblet cell depletion (score 01)