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Here, we use spatial transcriptomics (ST) to better understand the cellular specificity and complexity of different cell subsets involved in AITD and their possible pathogenic role
Alpha-lipoic acid: the metabolic antioxidant

It has been shown that this drug decreases the expression of DNMT1, 3A and 3B
Despite its promising anticancer properties, curcumin's clinical efficacy is significantly limited by its poor oral bioavailability, attributed to its low aqueous solubility, rapid metabolism, and systemic elimination (36)

Altmann C, Schmidt MHH (2018) The role of microglia in diabetic retinopathy: inflammation, microvasculature defects and neurodegeneration

Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo