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Finally, SOD3 requires copper-zinc as a cofactor and is located in the extracellular space

Oxidative stress and psychiatric disorders: evidence from the bidirectional mendelian randomization study

doi:10.1016/j.ydbio.2012.06.020

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The relationship of oxidation sensitivity of red blood cells and carbonic anhydrase activity in stored human blood: effect of certain phenolic compounds

It appears to act as a sleep-promoting neuromodulator rather than a sedative, normalizing disturbed sleep patterns without causing sedation or next-day impairment
