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J., Fielding C

Early intervention potentially most impactful for callus formation and revascularization

Diabetic patients are known to have a multifactorial hypercoagulable state related to increased inflammatory markers, and increased platelet aggregation (and indeed, an increased risk for downstream clinical effects such as stroke, heart attack, and other thrombotic events)

Mio K, Togo-Ohno M, Tadenuma N, Ogawa R, Yamanaka C, Aoe S