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For example, in primary cardiac cells, Cu 2+ increases the release of interleukin-6 (IL-6) and activates MAP kinases, which are linked to cardiac inflammation and hypertrophy [76]

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SARS-CoV-2 S-2P (comprising proline substitutions at residues K986 and V987) is used as the target antigen in three gene-based vaccine candidates (mRNA vaccines by Moderna/National Institute of Allergy and Infectious Diseases (NIAID) and BioNTech/Pfizer and a recombinant Ad26 vaccine by Janssen Pharmaceutical Companies) and a protein-based candidate (by Novavax) 4,86,87,88,89,90,91,92,93,94,95,96 (Table 1)

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Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase)