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Across neurons and glia, mitochondria provide bioenergetic support, regulate Ca 2+ dynamics and reactive oxygen species levels, influence neurotransmitter synthesis and turnover, and sustain quality control programmes that preserve cellular integrity

[44] [53] Infants and young children present with muscle weakness, cranial nerve deficits including hearing loss, sensory symptoms including sensory ataxia, feeding difficulties, and respiratory distress caused by a sensorimotor axonal neuropathy and cranial nerve pathology

We see many people our age who are starting to decline and feel that we are not seeing that in our own lives